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Enterolactone-13C3

CAT: 0804-HY-W778286-01Size: 2.5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W778286-01Size:2.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enterolactone-13C3 is the 13C-labeled Enterolactone. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity[1]. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis[2].
CAS Number
918502-72-4
UNSPSC
12352005
Target
Apoptosis; Endogenous Metabolite; Isotope-Labeled Compounds
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
OC1=CC=CC([13CH2][C@@H]([13C](OC2)=O)[C@H]2[13CH2]C3=CC(O)=CC=C3)=C1
Molecular Formula
C15 13C3H18O4
Molecular Weight
301.31
References & Citations
[1]Bigdeli B, et al. Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. Toxicol Appl Pharmacol. 2016;313:180-194.|[2]Mali AV, et al. Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial-mesenchymal transition. Cancer Biol Med. 2018;15 (2) :137-156.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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