Enterolactone (Standard)

• Description :

  Enterolactone (Standard) is the analytical standard of Enterolactone. This product is intended for research and analytical applications. Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity[1]. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis[2].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Endogenous Metabolite; Reference Standards

• Type :

  Reference compound

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease; Others

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/enterolactone-standard.html

• Smiles :

  O=C1OC[C@H](CC2=CC=CC(O)=C2)[C@H]1CC3=CC=CC(O)=C3

• Molecular Formula :

  C18H18O4

• Molecular Weight :

  298.33

• References & Citations :

  [1]Bigdeli B, et al. Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. Toxicol Appl Pharmacol. 2016;313:180-194.|[2]Mali AV, et al. Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial-mesenchymal transition. Cancer Biol Med. 2018;15 (2) :137-156.|[3]Bigdeli B, et al. Enterolactone: A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. Toxicol Appl Pharmacol. 2016;313:180-194.|[4]Mali AV, et al. Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial-mesenchymal transition. Cancer Biol Med. 2018;15 (2) :137-156.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [78473-71-9]