CF 1743-d7

• Description :

  CF 1743-d7 is the deuterium labeled Cf1743 (HY-107025) . Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) [1].

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

• Related Pathways :

  Cell Cycle/DNA Damage; Others

• Field of Research :

  Infection

• Smiles :

  O[C@H]1C[C@@H](O[C@@H]1CO)N2C=C3C(OC(C4=CC=C(C=C4)CCC([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])=C3)=NC2=O

• Molecular Formula :

  C22H19D7N2O5

• Molecular Weight :

  405.50

• References & Citations :

  [1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported