CF 1743-d7

• Description:

  CF 1743-d7 is the deuterium labeled Cf1743 (HY-107025) . Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) [1].

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds; Nucleoside Antimetabolite/Analog

• Related Pathways:

  Cell Cycle/DNA Damage; Others

• Field of Research:

  Infection

• Smiles:

  O[C@H]1C[C@@H] (O[C@@H]1CO) N2C=C3C (OC (C4=CC=C (C=C4) CCC ([2H]) (C ([2H]) (C ([2H]) ([2H]) [2H]) [2H]) [2H]) =C3) =NC2=O

• Molecular Formula:

  C22H19D7N2O5

• Molecular Weight:

  405.50

• References & Citations:

  [1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported