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Moroxydine (hydrochloride) -d8

CAT: 0804-HY-W713297Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W713297Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Moroxydine hydrochloride-d8 (ABOB hydrochloride-d8) is the deuterium labeled Moroxydine (ABOB) hydrochloride. Moroxydine hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels[1][2][3].
CAS Number
2469734-82-3
Product Name Alternative
ABOB hydrochloride-d8
UNSPSC
12352005
Target
Apoptosis; Caspase; HCV; HSV; Influenza Virus; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
N=C(N1C([2H])(C([2H])(OC([2H])(C1([2H])[2H])[2H])[2H])[2H])NC(N)=N.Cl
Molecular Formula
C6H6D8ClN5O
Molecular Weight
215.71
References & Citations
[1]Yu XB, et al. Moroxydine (ABOB) hydrochloride hydrochloride inhibits grass carp reovirus replication and suppresses apoptosis in Ctenopharyngodon idella kidney cells. Antiviral Res. 2016 Jul;131:156-65. |[2]Yu XB, et al. In vitro antiviral efficacy of Moroxydine (ABOB) hydrochloride hydrochloride and ribavirin against grass carp reovirus and giant salamander iridovirus. Dis Aquat Organ. 2016 Oct 27;121 (3) :189-199. |[3]Yu XB, et al. Effects of Moroxydine (ABOB) hydrochloride hydrochloride and ribavirin on the cellular growth and immune responses by inhibition of GCRV proliferation. Res Vet Sci. 2018 Apr;117:37-44.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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