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3-Methylguanine

CAT: 0804-HY-W588285-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W588285-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways[1].
CAS Number
2958-98-7
Product Name Alternative
3-MG
UNSPSC
12352005
Hazard Statement
H302-H319
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Purity
90.000000
Smiles
O=C1N=C(N(C)C2=C1NC=N2)N
Molecular Formula
C6H7N5O
Molecular Weight
165.15
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Bjelland S, et al. Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli. Nucleic Acids Res. 1993 May 11;21 (9) :2045-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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