3-Methylguanine

• Description :

  3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways[1].

• Product Name Alternative :

  3-MG

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H319

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Others

• Purity :

  90.000000

• Smiles :

  O=C1N=C(N(C)C2=C1NC=N2)N

• Molecular Formula :

  C6H7N5O

• Molecular Weight :

  165.15

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Bjelland S, et al. Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli. Nucleic Acids Res. 1993 May 11;21 (9) :2045-9.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [2958-98-7]