Decanoic acid-13C

• Description:

  Decanoic acid-13C is the 13C-labeled Decanoic acid (HY-W015309) . Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  C-Met/HGFR; Glutaminase; iGluR; Isotope-Labeled Compounds; Tyrosinase

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer; Metabolic Disease; Neurological Disease

• Purity:

  99.30

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCCC[13C](O)=O

• Molecular Formula:

  C9 13CH20O2

• Molecular Weight:

  173.26

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.|[2]Warren EC, et al. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling[J]. Proc Natl Acad Sci U S A. 2020 Sep 22;117 (38) :23617-23625.|[3]Yang MH, et al. Decanoic Acid Exerts Its Anti-Tumor Effects via Targeting c-Met Signaling Cascades in Hepatocellular Carcinoma Model[J]. Cancers (Basel) . 2023 Sep 22;15 (19) :4681.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [84600-66-8]