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Decanoic acid-13C

CAT: 0804-HY-W266188-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W266188-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Decanoic acid-13C is the 13C-labeled Decanoic acid. Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3].
CAS Number
84600-66-8
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR; Glutaminase; iGluR; Isotope-Labeled Compounds; Tyrosinase
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCC[13C](O)=O
Molecular Formula
C9 13CH20O2
Molecular Weight
173.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.|[2]Warren EC, et al. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling[J]. Proc Natl Acad Sci U S A. 2020 Sep 22;117 (38) :23617-23625.|[3]Yang MH, et al. Decanoic Acid Exerts Its Anti-Tumor Effects via Targeting c-Met Signaling Cascades in Hepatocellular Carcinoma Model[J]. Cancers (Basel) . 2023 Sep 22;15 (19) :4681.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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