BioA-IN-1

• Description :

  BioA-IN-1 (Compound 15) is an inhibitor of BioA, a key enzyme in the biotin synthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. BioA-IN-1 exhibits antibacterial activity but has no cytotoxicity[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Purity :

  99.24

• Smiles :

  O=C1OC2=C(C=C1C(C3=CC=CS3)=O)C=CC(N(CC)CC)=C2

• Molecular Formula :

  C18H17NO3S

• Molecular Weight :

  327.40

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Park SW, et al. Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis. Chem Biol. 2015 Jan 22;22 (1) :76-86.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [77820-11-2]