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Tartronic acid

CAT: 0804-HY-W012865Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W012865Size:1 Each
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Description
Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research[1].
CAS Number
80-69-3
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; FABP; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Purity
98.0
Smiles
OC(C(O)=O)C(O)=O
Molecular Formula
C3H4O5
Molecular Weight
120.06
Precautions
H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
PPARγ

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