2-Fluoroadenosine (Standard)

CAT: 0804-HY-W011517R-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W011517R-01Size:10 mg
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Description
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions[1][2].
CAS Number
[146-78-1]
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(F)N=C3N)=C3N=C2)O[C@@H]1CO
Molecular Formula
C10H12FN5O4
Molecular Weight
285.24
References & Citations
[1]Arai T, et al. In vitro assessment of anticryptosporidial efficacy and cytotoxicity of adenosine analogues using a SYBR Green real-time PCR method. J Antimicrob Chemother. 2011 Mar;66 (3) :560-3. |[2]Reddy MCM, et al. High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme. J Biol Chem. 2007 Sep 14;282 (37) :27334-27342.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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