2-Fluoroadenosine

• Description:

  2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions[1][2].

• Product Name Alternative:

  2FA

• UNSPSC:

  12352200

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Parasite

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2-fluoroadenosine.html

• Purity:

  99.82

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](O)[C@H](N2C(N=C(F)N=C3N)=C3N=C2)O[C@@H]1CO

• Molecular Formula:

  C10H12FN5O4

• Molecular Weight:

  285.24

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Arai T, et al. In vitro assessment of anticryptosporidial efficacy and cytotoxicity of adenosine analogues using a SYBR Green real-time PCR method. J Antimicrob Chemother. 2011 Mar;66 (3) :560-3. |[2]Reddy MCM, et al. High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme. J Biol Chem. 2007 Sep 14;282 (37) :27334-27342.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  [146-78-1]