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2-Fluoroadenosine

CAT: 0804-HY-W011517-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W011517-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antiparasite activity with EC50 value of 0.842 mM for Cryptosporidium parvum. 2-Fluoroadenosine has a highly specific structural basis for MtADK. 2-Fluoroadenosine is commonly used in the study of parasitic conditions[1][2].
CAS Number
146-78-1
Product Name Alternative
2FA
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2-fluoroadenosine.html
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1[C@@H](O)[C@H](N2C(N=C(F)N=C3N)=C3N=C2)O[C@@H]1CO
Molecular Formula
C10H12FN5O4
Molecular Weight
285.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Arai T, et al. In vitro assessment of anticryptosporidial efficacy and cytotoxicity of adenosine analogues using a SYBR Green real-time PCR method. J Antimicrob Chemother. 2011 Mar;66 (3) :560-3. |[2]Reddy MCM, et al. High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme. J Biol Chem. 2007 Sep 14;282 (37) :27334-27342.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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