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DMPX

CAT: 0804-HY-W004425-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W004425-01Size:5 mg
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Description
DMPX (3,7-Dimethyl-1-propargylxanthine) is a BBB-penetrable caffeine analogue. DMPX is A2 selective adenosine receptor (AR) antagonist that strongly and selectively blocks hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists such as NECA. DMPX can be used in the study of Parkinson's disease and other diseases[1][2].
CAS Number
14114-46-6
Product Name Alternative
3,7-Dimethyl-1-propargylxanthine
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Concentration
10mM
Purity
99.66
Solubility
DMSO : 40 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N(C)C(N1CC#C)=O)N=CN2C
Molecular Formula
C10H10N4O2
Molecular Weight
218.21
Precautions
H315, H319, H335
References & Citations
[1]Müller CE, et al. Synthesis and structure-activity relationships of 3,7-dimethyl-1-propargylxanthine derivatives, A2A-selective adenosine receptor antagonists. J Med Chem. 1997 Dec 19;40 (26) :4396-405.|[2]Seale TW, et al. 3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. Life Sci. 1988;43 (21) :1671-84.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

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T204595-01DMPX
MBS6116611-013,7-Dimethyl-1-propargylxanthine (DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine)
D3693-553,7-Dimethyl-1-propargylxanthine (DMPX, 3,7-Dimethyl-1- (2-propynyl) xanthine)

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