PEG2000-DMPE

• Description :

  PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20[1].

• UNSPSC :

  12352211

• Target :

  Liposome

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/peg2000-dmpe.html

• Purity :

  99.70

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CCCCCCCCCCCCCC(O[C@](COP(OCCNC(OCCOC)=O)(O)=O)([H])COC(CCCCCCCCCCCCC)=O)=O

• Molecular Formula :

  C125H248NO55P

• Molecular Weight :

  2676.25

• References & Citations :

  [1]Han I, et al. Enhanced antitumor activity [correction for activitiy] of trans (+/-) -1,2-diaminocyclo- hexaneglutamatoplatinum (II) formulated with stealth liposome. Bioorg Med Chem. 2003 Dec 1;11 (24) :5443-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported