PEG2000-DMPE

• UNSPSC Description:

  PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20[1].

• Target Antigen:

  Liposome

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/peg2000-dmpe.html

• Purity:

  95.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCCCCCCCC(O[C@](COP(OCCNC(OCCOC)=O)(O)=O)([H])COC(CCCCCCCCCCCCC)=O)=O

• Molecular Weight:

  2676.25

• References & Citations:

  [1]Han I, et al. Enhanced antitumor activity [correction for activitiy] of trans(+/-)-1,2-diaminocyclo- hexaneglutamatoplatinum(II) formulated with stealth liposome. Bioorg Med Chem. 2003 Dec 1;11(24):5443-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported