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5-Hydroxyoxindole (Standard)

CAT: 0804-HY-W001542RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W001542RSize:1 Each
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Description
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders[1][2].
CAS Number
[3416-18-0]
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Smiles
O=C1NC2=C(C=C(O)C=C2)C1
Molecular Formula
C8H7NO2
Molecular Weight
149.15
References & Citations
[1]Daisuke Yasuda, et al. Preparation and antioxidant/pro-oxidant activities of 3-monosubstituted 5-hydroxyoxindole derivatives.|[2]Papy-García, D., et al., (2003) . Detection and quantification of 5-hydroxyoxindole in mammalian sera and tissues by high performance liquid chromatography with multi-electrode electrochemical detection. Clinical biochemistry, 36 (3), 215–220.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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