MK-1966

• Description :

  MK-1966 is a humanized monoclonal antibody inhibitor targeting interleukin-10 (IL-10) . MK-1966 blocks the inhibitory effects of IL-10 on immune cells such as macrophages and dendritic cells to restore anti-tumor immune responses. MK-1966 is promising for research of cancers[1].

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Interleukin Related

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  96.17

• Smiles :

  [MK-1966]

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Phan U, et al. Development of the anti-IL-10 mAb MK-1966 in combination with in situ vaccination of a TLR9 agonist SD-101 for cancer immunotherapy[J]. European Journal of Cancer, 2016, 69: S91-S92.

• Shipping Conditions :

  Dry Ice

• Storage Conditions :

  -80°C

• Scientific Category :

  Inhibitory Antibodies

• Clinical Information :

  Phase 1

• Isoform :

  IL-10