SAR-442257

• Description:

  SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and CD28 on multiple myeloma cells and co-stimulates CD3 and CD28 on T cells[1].

• UNSPSC:

  12352203

• Target:

  CD28; CD3; CD38

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Purity:

  99.0

• Smiles:

  [*]S[R442257]

• Molecular Weight:

  (145.44 kDa)

• References & Citations:

  [1]Grab AL, et al. Pre-Clinical Assessment of SAR442257, a CD38/CD3xCD28 Trispecific T Cell Engager in Treatment of Relapsed/Refractory Multiple Myeloma. Cells. 2024 May 20;13 (10) :879.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C

• Scientific Category:

  Inhibitory Antibodies

• Clinical Information:

  Phase 1