SAR-115740

CAT: 0804-HY-105690Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-105690Size:1 Each
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Description
SAR-115740 is a TRPV1 antagonist. SAR-115740 exhibits developmental toxicity in H9 cell experiments. SAR-115740 can be used for research on inflammatory conditions or neurological disorders[1].
CAS Number
[1253734-75-6]
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC4=CC(F)=CC=C4N3CC5=CC(F)=CC=C5
Molecular Formula
C24H17F2N3O
Molecular Weight
401.41
References & Citations
[1]Khairatkar-Joshi N, et al. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol Med. 2009 Jan;15 (1) :14-22. |[2]Zurlinden TJ, et al. Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity. Toxicol Sci. 2020 Apr 1;174 (2) :189-209.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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