SAR-115740

• Description:

  SAR-115740 is a TRPV1 antagonist. SAR-115740 exhibits developmental toxicity in H9 cell experiments. SAR-115740 can be used for research on inflammatory conditions or neurological disorders[1].

• UNSPSC:

  12352005

• Target:

  TRP Channel

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  O=C(NC1=CC=C(NC=C2)C2=C1)C3=CC4=CC(F)=CC=C4N3CC5=CC(F)=CC=C5

• Molecular Formula:

  C24H17F2N3O

• Molecular Weight:

  401.41

• References & Citations:

  [1]Khairatkar-Joshi N, et al. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol Med. 2009 Jan;15 (1) :14-22. |[2]Zurlinden TJ, et al. Profiling the ToxCast Library With a Pluripotent Human (H9) Stem Cell Line-Based Biomarker Assay for Developmental Toxicity. Toxicol Sci. 2020 Apr 1;174 (2) :189-209.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1253734-75-6]