SAR-150640

• Description:

  SAR-150640, a selective β3-adrenoceptor agonist, prevents the increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis[1].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sar-150640.html

• Smiles:

  CCOC(C1=CC=C([C@@H]2CC[C@H](CC2)NC[C@H](O)COC3=CC(NS(C)(=O)=O)=C(C=C3)O)C=C1)=O.Cl

• Molecular Formula:

  C25H35ClN2O7S

• Molecular Weight:

  543.07

• References & Citations:

  [1]F Lirussi, et al. SAR150640, a selective beta3-adrenoceptor agonist, prevents human myometrial remodelling and activation of matrix metalloproteinase in an in vitro model of chorioamnionitis. Br J Pharmacol. 2010 Mar;159 (6) :1354-66.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  β adrenergic receptor

• CAS Number:

  [433212-21-6]