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SAR-150640

CAT: 0804-HY-169340Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169340Size:1 Each
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Description
SAR-150640, a selective β3-adrenoceptor agonist, prevents the increase in MMP activity and production observed after LPS stimulation or in cases of chorioamnionitis[1].
CAS Number
433212-21-6
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sar-150640.html
Smiles
CCOC(C1=CC=C([C@@H]2CC[C@H](CC2)NC[C@H](O)COC3=CC(NS(C)(=O)=O)=C(C=C3)O)C=C1)=O.Cl
Molecular Formula
C25H35ClN2O7S
Molecular Weight
543.07
References & Citations
[1]F Lirussi, et al. SAR150640, a selective beta3-adrenoceptor agonist, prevents human myometrial remodelling and activation of matrix metalloproteinase in an in vitro model of chorioamnionitis. Br J Pharmacol. 2010 Mar;159 (6) :1354-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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