RG-6333

CAT: 0804-HY-P991176-01Size: 1 mgDry Ice: YesHazardous: No
CAT#:0804-HY-P991176-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
RG-6333 is a bispecific agonist targeting CD19 and CD28. RG-6333 specifically recognizes and binds to the CD19 antigen on the surface of B-cell malignancies to locate tumor cells. RG-6333 activates T cells by binding to CD28, overcoming activation barriers to enhance anti-tumor immunity. RG-6333 can be used in the study of relapsed/refractory non-Hodgkin's lymphoma. The recommended isotype control is human IgG1 kappa, isotype control (HY-P99001) [1][2].
Product Name Alternative
RO7443904
UNSPSC
12352203
Target
CD19; CD28
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.05
Smiles
[RG-6333]
References & Citations
[1]Sam J, et al. CD19-CD28: an affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy. Blood. 2024 May 23;143 (21) :2152-2165.|[2]Sam J, et al. RG6333 (CD19-CD28), a CD19-targeted affinity-optimized CD28 bispecific antibody, enhances and prolongs the anti-tumor activity of glofitamab (CD20-TCB) in preclinical models. Blood 140.Supplement 1 (2022) : 3142-3143.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1

Related Products

CatalogName
HY-179566CHF-6333
HY-132600RG-101
HY-19190RG-201
HY-43057-01IBu-rG
HY-P990658-01RG-7652
HY-164248-01Ac-rG
HY-116138RG-14467
HY-171328-01RG-15
HY-P990656-01RG-6125
HY-118175RG 14921

Alternative Products

CatalogName
MF-0101380-01RG-6333
HB996013-01Anti-CD19 & CD28 Bispecific Recombinant Antibody (RG-6333)
MF-0111395-01CHF-6333
MF-0111391-01CHF-6333 CATION
MBS3607970-01RG 14620
MBS516365-01RG-108
MBS5799843RG-101
MBS5813662RG 12915
MBS579487RG-7112
MBS5778207RG 7152

Popular Products