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GSK-3174998

CAT: 0804-HY-P991052-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P991052-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK-3174998 is a humanized IgG1 OX40/TNFRSF4 agonistic monoclonal antibody. GSK-3174998 has the potential for the study of advanced solid tumors. The isotype control for GSK-3174998 can refer to Human IgG1 kappa, Isotype Control.
CAS Number
2089398-68-3
UNSPSC
12352203
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.81
Smiles
[GSK-3174998]
Molecular Weight
(147.197 kDa)
References & Citations
[1]Postel-Vinay S, et al. First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1) . J Immunother Cancer. 2023 Mar;11 (3) :e005301.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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