GnRH antagonist 3

• Description:

  GnRH antagonist 3 (Compound 11) is a GnRH antagonist with an IC50 of 7 nM. GnRH antagonist 3 can be used in the research of hormone-dependent diseases[1].

• UNSPSC:

  12352209

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  GnRH Receptor

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  ClC (C=C1) =CC=C1C[C@@H] (NC ([C@H] (NC (C) =O) CC2=CC3=C (C=CC=C3) C=C2) =O) C (N[C@H] (CC4=CC=CC=N4) C (NCC (N[C@@H] (CCCNC (N) =N) C (N5[C@@H] (CCC5) C (N[C@H] (C) C (N) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C48H59ClN12O8

• Molecular Weight:

  967.51

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Yahalom D, et al. Design and synthesis of potent hexapeptide and heptapeptide gonadotropin-releasing hormone antagonists by truncation of a decapeptide analogue sequence. J Med Chem. 2000 Jul 27;43 (15) :2831-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  292141-31-2