GnRH antagonist 3

• Description :

  GnRH antagonist 3 (Compound 11) is a GnRH antagonist with an IC50 of 7 nM. GnRH antagonist 3 can be used in the research of hormone-dependent diseases[1].

• UNSPSC :

  12352209

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  GnRH Receptor

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Smiles :

  ClC(C=C1)=CC=C1C[C@@H](NC([C@H](NC(C)=O)CC2=CC3=C(C=CC=C3)C=C2)=O)C(N[C@H](CC4=CC=CC=N4)C(NCC(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N[C@H](C)C(N)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C48H59ClN12O8

• Molecular Weight :

  967.51

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Yahalom D, et al. Design and synthesis of potent hexapeptide and heptapeptide gonadotropin-releasing hormone antagonists by truncation of a decapeptide analogue sequence. J Med Chem. 2000 Jul 27;43 (15) :2831-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [292141-31-2]