PSM-mec peptide

• Description:

  PSM-mec peptide is a peptide toxin belonging to the phenol-soluble modulin (PSM) superfamily. PSM-mec peptide is encoded by the psm-mec gene and associated with the methicillin resistance gene element (SCCmec) . PSM-mec peptide has pro-inflammatory, cytolytic functions and the role of regulating the structure of biofilms. PSM-mec peptide can be mainly used for the pathogenic mechanism and drug resistance research of canine pseudo-intermediate Staphylococcus (S. pseudintermedius) related infections and zoonotic diseases[1].

• UNSPSC:

  12352209

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Purity:

  98.61

• Solubility:

  DMSO : 20 mg/mL (ultrasonic)

• Smiles:

  O=CN[C@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](C(N[C@]([C@H](O)C)([H])C(NCC(N[C@@H](C(C)C)C(N[C@@]([C@@H](C)CC)(C(N[C@@]([C@H](O)C)(C(N[C@H](CO)C(N[C@@]([C@@H](C)CC)(C(N[C@@]([C@@H](C)CC)(C(N[C@@H](CC(O)=O)C(N[C@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(N[C@H](CCCCN)C(N[C@@]([C@@H](C)O)(C(N[C@H](CS)C(N[C@@]([C@@H](C)CC)(C(N[C@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C(NCC=O)=O)CC1=CC=CC=C1)=O)=O)=O)[H])=O)=O)[H])=O)=O)=O)=O)=O)[H])=O)[H])=O)=O)[H])=O)[H])=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O

• Molecular Formula:

  C109H176N24O32S2

• Molecular Weight:

  2414.86

• References & Citations:

  [1]Cheung GYC, et al. Methicillin Resistance Elements in the Canine Pathogen Staphylococcus pseudintermedius and Their Association with the Peptide Toxin PSM-mec. Antibiotics (Basel) . 2024 Jan 28;13 (2) :130.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1708928-71-5]