AC-SDKP-NH2

CAT: 0804-HY-P11297Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P11297Size:1 Each
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Description
AC-SDKP-NH2 is a substrate peptide of Angiotensin converting enzyme (ACE) . AC-SDKP-NH2 has anti-inflammatory and anti-fibrotic activities. AC-SDKP-NH2 directly acts on tissues and prevents or reverses them from excessive fibrosis, but fails to reduce blood pressure and left ventricular hypertrophy (LVH) . AC-SDKP-NH2 attenuates inflammation and cell differentiation, proliferation and migration, therefore reducing fibrosis in the heart, vessels and kidneys in mice model. AC-SDKP-NH2 can be used for cardiovascular diseases such as hypertension research[1].
CAS Number
[194484-75-8]
UNSPSC
12352209
Target
Angiotensin-converting Enzyme (ACE)
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
CC(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N)=O)=O)=O)=O)=O
Molecular Formula
C20H34N6O8
Molecular Weight
486.52
References & Citations
[1]Hrenak J, et al. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) : Potential target molecule in research of heart, kidney and brain. Curr Pharm Des. 2015;21 (35) :5135-43.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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