Ac-GpYLPQTV-NH2

• UNSPSC Description:

  Ac-GpYLPQTV-NH2 is a STAT3 inhibitor with an IC50 value of 0.33 μM. Ac-GpYLPQTV-NH2 has antitumor activity[1].

• Target Antigen:

  STAT

• Type:

  Peptides

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ac-gpylpqtv-nh2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(N)=O)NC([C@H]1N(CCC1)C([C@H](CC(C)C)NC([C@@H](NC(CNC(C)=O)=O)CC2=CC=C(C=C2)OP(O)(O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  897.91

• References & Citations:

  [1]Uehara Y, et al A. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009 Mar 13;380(3):627-31.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1349616-70-1