IL13Rα2 D1

• Description:

  IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer[1].

• UNSPSC:

  12352209

• Target:

  Akt; ERK; FAK; Interleukin Related; MMP; Src

• Related Pathways:

  Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Field of Research:

  Cancer

• Smiles:

  O=C (N[C@@H] (CO) C (N[C@@H] (CCC (O) =O) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (CC1=CNC2=CC=CC=C12) C (N[C@@H] (CCCCN) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (CCCCN) C (N[C@@H] (CC (N) =O) C (O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) CN

• Molecular Formula:

  C61H100N16O20

• Molecular Weight:

  1377.54

• References & Citations:

  [1]Bartolomé RA, et al. An IL13Rα2 peptide exhibits therapeutic activity against metastatic colorectal cancer. Br J Cancer. 2018 Oct;119 (8) :940-949.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  IL-13

• CAS Number:

  2319573-67-4