2-Deoxy-D-glucose-d1

2-Deoxy-D-glucose-d1

• CAS Number: 188004-07-1
• UNSPSC Description: 2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
• Target Antigen: Apoptosis; Hexokinase; HSV; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Apoptosis;Metabolic Enzyme/Protease;Others
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Solubility: H2O : 250 mg/mL (ultrasonic)
• Smiles: O=C([2H])C[C@@H](O)[C@H](O)[C@H](O)CO
• Molecular Weight: 165.16
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.;Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported