Poneratoxin (acetate)

CAT: 0804-HY-P10234A-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P10234A-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Poneratoxin acetate is the acetate salt form of Poneratoxin (HY-P10234) . Poneratoxin acetate is the modulator for voltage-gated sodium channel (NaV, EC50 for NaV1.6 and NaV1.7 is 97 nM and 2.3 µM), that lowers the voltage threshold for activation and inhibits the inactivation of channels, enhances the excitability of neurons, and leads to the transmission of pain signals[1].
UNSPSC
12352209
Target
Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
98.77
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC(C)C)C(N1[C@@H](CCC1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H]([C@H](O)C)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CC=CC=C5)N.CC(O)=O.[x]
Molecular Formula
C129H215N33O31S.xC2H4O2
Molecular Weight
2756.35 (free base)
References & Citations
[1]Robinson SD, et al., Ant venoms contain vertebrate-selective pain-causing sodium channel toxins. Nat Commun. 2023 May 23;14 (1) :2977.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
PLoS Biol. 2025 Nov 24;23 (11) :e3003513.|Bioorg Med Chem. 2025 Oct 9:132:118436.|Sci Rep. 2025 Jul 16;15 (1) :25854.

Related Products

CatalogName
HY-P10234Poneratoxin
HY-166875SApramycin acetate-d7 (acetate)
HY-134716Methyl acetate-PEG1-methyl acetate
HY-W127616-01β-Sitosterol acetate, 40% (contains Campesterol acetate)
HY-12555Gonadorelin (acetate)
HY-W289164Nonyl acetate
HY-N1309Simiarenol acetate
HY-100866BF1324 (acetate)
HY-B0137BPrilocaine (acetate)
HY-N13323Ylangenyl acetate

Alternative Products

CatalogName
MF-0108538Poneratoxin acetate
MF-0126386-01Poneratoxin
MBS1192453-01Recombinant Paraponera clavata Poneratoxin
MBS641115-01Vitamin A Acetate (Retinol Acetate, Retinyl Acetate)
3121815Cupric acetate (copper acetate)
3121685Copper acetate (Cupic acetate)
3121630Cobalt acetate (Cobaltous acetate)
RM-L052100-01Leuprolide Acetate (Leuprorelin Acetate)
MA-0130Acetate
1131100 100Mercuric Acetate (Mercury (II) Acetate)

Popular Products