F 991

• Description :

  F 991 is an immunoglobulin free light chain antagonist. F 991 can significantly reduce the levels of pro-inflammatory cytokines (TNF-α and IL-6) . F 991 can be used for research on allergic conditions[1].

• UNSPSC :

  12352209

• Target :

  Interleukin Related; TNF Receptor

• Related Pathways :

  Apoptosis; Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  CC(C)C[C@@H](C(O)=O)NC([C@H](CS)NC([C@H](CS)NC([C@H](CC1=CNC=N1)NC(CNC([C@H](CO)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@H](CC4=CNC=N4)NC([C@H](C)N)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C43H60N14O11S2

• Molecular Weight :

  1013.15

• References & Citations :

  [1]van Houwelingen AH, et al. Topical application of F991, an immunoglobulin free light chain antagonist, prevents development of contact sensitivity in mice. Clin Exp Allergy. 2007 Feb;37 (2) :270-5.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  IL-6

• CAS Number :

  [188193-59-1]