Chebulic acid (Standard)

• Description:

  Chebulic acid (Standard) is the analytical standard of Chebulic acid (HY-N4170) . This product is intended for research and analytical applications. Chebulic acid is a phenolic acid compound isolated from Terminalia chebula with strong antioxidant activity, which breaks protein cross-links induced by advanced glycation end products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress, and liver damage, supporting its beneficial role in asthma, diabetes, and liver protection[1][2][3][4][5].

• Target:

  Keap1-Nrf2; Reactive Oxygen Species (ROS) ; Reference Standards

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C ([C@@H] (CC (O) =O) [C@H] ([C@H] (O1) C (O) =O) C2=C (C (O) =C (C=C2C1=O) O) O) O

• Molecular Formula:

  C14H12O11

• Molecular Weight:

  356.24

• References & Citations:

  [1]Lee KW, et al. Protective effects of chebulic acid on alveolar epithelial damage induced by urban particulate matter. BMC Complement Altern Med. 2017 Jul 19;17 (1) :373.|[2]Silawat N, et al. Chebulic acid attenuates ischemia reperfusion induced biochemical alteration in diabetic rats. Pharm Biol. 2013 Jan;51 (1) :23-9.|[3]Lee H S, et al. Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction[J]. Journal of Ethnopharmacology, 2010, 131 (3) : 567-574.|[4]Lee H S, et al. Isolation of chebulic acid from Terminalia chebula Retz. and its antioxidant effect in isolated rat hepatocytes[J]. Archives of Toxicology, 2007, 81: 211-218.|[5]Feng X H, et al. In vivo hepatoprotective activity and the underlying mechanism of chebulinic acid from Terminalia chebula fruit[J]. Phytomedicine, 2021, 83: 153479.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  23725-05-5