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Atraric acid (Standard)

CAT: 0804-HY-N2908R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2908R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Atraric acid (Standard) is the analytical standard of Atraric acid. This product is intended for research and analytical applications. Atraric acid (Methyl atrarate) is a specific androgen receptor (AR) antagonist with anti-inflammatory and anticancer effects. Atraric acid represses the expression of the endogenous prostate specific antigen gene in both LNCaP and C4-2 cells. Atraric acid can also inhibit the synthesis of NO and cytokine, and suppress the MAPK-NFκB signaling pathway. Atraric acid can be used to research prostate diseases and inflammatory diseases[1][2].
CAS Number
4707-47-5
Product Name Alternative
Methyl atrarate (Standard)
UNSPSC
12352005
Target
Androgen Receptor; NF-κB; NO Synthase; p38 MAPK; Reference Standards
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; NF-κB; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(OC)C1=C(C)C=C(O)C(C)=C1O
Molecular Formula
C10H12O4
Molecular Weight
196.20
References & Citations
[1]Roell D, Baniahmad A. The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth. Mol Cell Endocrinol. 2011 Jan 30;332 (1-2) :1-8.|[2]Papaioannou M, et al. The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth. J Cell Mol Med. 2009 Aug;13 (8B) :2210-2223.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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