(Rac) -8-Gingerol

• Description:

  (Rac) -8-Gingerol is a non-volatile component. (Rac) -8-Gingerol can be extracted from ginger. (Rac) -8-Gingerol enhances Apoptosis. (Rac) -8-Gingerol decreases the level of phosphorylated EGFR and, accordingly, the phosphorylation levels of its downstream effectors, STAT3 and ERK. (Rac) -8-Gingerol exhibits anticancer activity against colorectal cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; EGFR; PERK; STAT

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  O=C (CC (CCCCCCC) O) CCC1=CC=C (C (OC) =C1) O

• Molecular Formula:

  C19H30O4

• Molecular Weight:

  322.44

• References & Citations:

  [1]Hu SM, et al. 8 Gingerol regulates colorectal cancer cell proliferation and migration through the EGFR/STAT/ERK pathway. Int J Oncol. 2020 Jan;56 (1) :390-397.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  STAT3

• CAS Number:

  77398-92-6