[6]-Gingerol

• UNSPSC Description:

  [6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

• Target Antigen:

  AMPK; Apoptosis

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Epigenetics;PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/[6]-Gingerol.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  CCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O

• Molecular Weight:

  294.39

• References & Citations:

  [1]Radhakrishnan EK, et al. [6]-Gingerol induces caspase-dependent apoptosis and prevents PMA-induced proliferation in colon cancer cells by inhibiting MAPK/AP-1 signaling. PLoS One. 2014 Aug 26;9(8):e104401.|[2]Chang KW, et al. 6-Gingerol modulates proinflammatory responses in dextran sodium sulfate (DSS)-treated Caco-2 cells and experimental colitis in mice through adenosine monophosphate-activated protein kinase (AMPK) activation. Food Funct. 2015 Oct;6(10):3334-41.|[3]Fan J, et al. 6-Gingerol inhibits osteosarcoma cell proliferation through apoptosis and AMPK activation. Tumour Biol. 2015 Feb;36(2):1135-41.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  23513-14-6