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Bruceoside D

CAT: 0804-HY-N16507Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N16507Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bruceoside D is a cytotoxic quassinoid glucoside found in Brucea javanica. Bruceoside D is a microtubule polymerization inhibitor. Bruceoside D demonstrates inhibitory activity against leukemia (CCRF-CEM), non-small cell lung cancer (A549), and ovarian cancer (OVCAR-3) cell lines. Bruceoside D is promising for research of cancers[1].
CAS Number
[167782-22-1]
UNSPSC
12352005
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
OC([C@@]1([C@H]2O)[C@@]([C@H]3OC(/C=C(C)/C)=O)([H])[C@@]([C@@](OC3=O)([H])C[C@@]4([H])[C@@H](C5=O)C)(CO1)[C@@]([C@H]2O)([H])[C@]4(C=C5O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)C)=O
Molecular Formula
C31H40O16
Molecular Weight
668.64
References & Citations
[1]Ohnishi S, et al. Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica. J Nat Prod. 1995 Jul;58 (7) :1032-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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