Bruceoside D

• Description :

  Bruceoside D is a cytotoxic quassinoid glucoside found in Brucea javanica. Bruceoside D is a microtubule polymerization inhibitor. Bruceoside D demonstrates inhibitory activity against leukemia (CCRF-CEM), non-small cell lung cancer (A549), and ovarian cancer (OVCAR-3) cell lines. Bruceoside D is promising for research of cancers[1].

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Field of Research :

  Cancer

• Smiles :

  OC([C@@]1([C@H]2O)[C@@]([C@H]3OC(/C=C(C)/C)=O)([H])[C@@]([C@@](OC3=O)([H])C[C@@]4([H])[C@@H](C5=O)C)(CO1)[C@@]([C@H]2O)([H])[C@]4(C=C5O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]([C@H]6O)CO)C)=O

• Molecular Formula :

  C31H40O16

• Molecular Weight :

  668.64

• References & Citations :

  [1]Ohnishi S, et al. Bruceosides D, E, and F, three new cytotoxic quassinoid glucosides from Brucea javanica. J Nat Prod. 1995 Jul;58 (7) :1032-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [167782-22-1]