Cassiaside C2

• Description :

  Cassiaside C2 is a naphthopyrone with a strong antiallergic activity. Cassiaside C2 inhibits the histamine release from rat peritoneal exudate mast cells induced by antigen-antibody reaction[1][2].

• CAS Number :

  [218155-49-8]

• UNSPSC :

  12352005

• Target :

  Histamine Receptor

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  OC1=C(C(OC(C)=C2)=O)C2=CC3=C1C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)O)=CC(OC)=C3

• Molecular Formula :

  C39H52O25

• Molecular Weight :

  920.82

• References & Citations :

  [1]Zhang Z, et al. Total synthesis of the antiallergic naphtho-alpha-pyrone tetraglucoside, cassiaside C (2), isolated from cassia seeds. J Org Chem. 2003 Aug 8;68 (16) :6309-13. |[2]Kitanaka S, et al. Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of Cassia obtusifolia L. Chem Pharm Bull (Tokyo) . 1998 Oct;46 (10) :1650-2.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported