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Cassiaside

CAT: 804-HY-N7887-01Size: 1 mgDry Ice: NoHazardous: No
1 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cassiaside is a naphthopyrone glucoside, shows mixed-type inhibition against BACE1 (IC50=4.45 μM; Ki=9.85 μM) . Cassiaside possesses potential anti- Alzheimer's disease (AD) activity[1].
CAS Number
[13709-03-0]
UNSPSC
12352005
Target
Beta-secretase
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cassiaside.html
Purity
99.67
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=C(C2=O)C(OC(C)=C2)=CC3=C1C(O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)=CC(O)=C3
Molecular Formula
C20H20O10
Molecular Weight
420.37
References & Citations
[1]Jung HA, et al. Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases. J Ethnopharmacol. 2016;191:152-160.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
BACE1

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