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Concanamycin F

CAT: 0804-HY-N14426Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14426Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Concanamycin F has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase (Ki=0.02 nM), which is an important tool for biochemical research[1].
CAS Number
144539-92-4
UNSPSC
12352005
Target
Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C1O[C@H]([C@@H](C)[C@@H](O)[C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H](/C=C/C)O2)C)[C@@H](OC)/C=C/C=C(C)/C[C@@H](C)[C@H](O)[C@H](CC)[C@H](O)[C@H](C)/C=C(C)/C=C1\OC
Molecular Formula
C39H64O10
Molecular Weight
692.92
References & Citations
[1]I Paterson I, et al. Total Synthesis of (+) -Concanamycin F We thank the EPSRC (GR/K54052), Knoll Pharmaceuticals (CASE Studentship to V.A.D.), the Cambridge Commonwealth Trust (M.D.M.), and Merck for support, and Dr R. Norrie (Knoll Pharmaceuticals) for helpful discussions. We also thank Prof. A. Zeeck (Göttingen) for kindly providing copies of (1) H NMR spectra of concanamycin F (concanolide A) . Angew Chem Int Ed Engl. 2000 Apr;39 (7) :1308-1312.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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