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ER-Tracker Blue-White DPX (solution)

CAT: 0804-HY-DY1074-01Size: 50 μLDry Ice: NoHazardous: No
CAT#:0804-HY-DY1074-01Size:50 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation[1].Solvent and concentration: DMSO: 1 mM
CAS Number
[287715-95-1]
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
O=S(C(C=C1)=CC=C1C(O2)=NC=C2C3=CC=C(N(C)C)C=C3)(NCCNC(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O
Molecular Formula
C26H21F5N4O4S
Molecular Weight
580.53
References & Citations
[1]Tanuja T Merianda, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40 (2) :128-42.|[2]Corryn E Chini, et al. Observation of endoplasmic reticulum tubules via TOF-SIMS tandem mass spectrometry imaging of transfected cells. Biointerphases. 2018 Feb 26;13 (3) :03B409.|[3]Yun-Mi Jeong, et al. CDy6, a photostable probe for long-term real-time visualization of mitosis and proliferating cells. Chem Biol. 2015 Feb 19;22 (2) :299-307.|[4]Merianda TT, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40 (2) :128-42.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 1 year, protect from light. Avoid repeated freezing and thawing
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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