ER-Tracker Blue-White DPX

ER-Tracker Blue-White DPX

• CAS Number: 287715-95-1
• UNSPSC Description: ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation[1].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/er-tracker-blue-white-dpx.html
• Purity: 96.35
• Solubility: DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=S(C(C=C1)=CC=C1C(O2)=NC=C2C3=CC=C(N(C)C)C=C3)(NCCNC(C4=C(F)C(F)=C(F)C(F)=C4F)=O)=O
• Molecular Weight: 580.53
• References & Citations: [1]Corryn E Chini, et al. Observation of endoplasmic reticulum tubules via TOF-SIMS tandem mass spectrometry imaging of transfected cells. Biointerphases. 2018 Feb 26;13(3):03B409.|[2]Yun-Mi Jeong, et al. CDy6, a photostable probe for long-term real-time visualization of mitosis and proliferating cells. Chem Biol. 2015 Feb 19;22(2):299-307.|[3]Merianda TT, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40(2):128-42.|[4]Tanuja T Merianda, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40(2):128-42.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported