BIN-3

• Description :

  BIN-3 is a novel near-infrared fluorescent probe. BIN-3 has excellent biocompatibility, no cytotoxicity, and no hemolysis. BIN-3 can be used for highly sensitive and selective imaging of drug-resistant bacterial infections expressing β-lactam enzymes in live mice[1].

• CAS Number :

  [3086791-47-8]

• UNSPSC :

  12352005

• Target :

  Bacterial; Fluorescent Dye

• Related Pathways :

  Anti-infection; Others

• Field of Research :

  Infection

• Smiles :

  CCC[N+]1=C(C(C)(C2=CC=CC=C21)C)/C=C/C3=C4OC5=C(C=C4CCC3)C=C(C(OCC6=C(N7C([C@H]([C@H]7SC6)NC(CCC8=CN(N=N8)CC[N+](C)(CCCS(=O)([O-])=O)C)=O)=O)C(O)=O)=C5)COC(NCC)=O.[I-]

• Molecular Formula :

  C52H65IN8O11S2

• Molecular Weight :

  1169.15

• References & Citations :

  [1]Chen F, et al. Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity-Switching, Self-Immobilizing, Near-Infrared Fluorogenic β-Lactamase Probe Enriched within Bacteria. Adv Sci (Weinh) . 2025 Feb;12 (5) :e2408559.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported