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Quinapril

CAT: 0804-HY-B0477ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-B0477ASize:1 Each
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Description
Quinapril is a potent, orally active, non-peptide and nonsulfhydryl inhibitor of angiotensin-converting enzyme (ACE) . Quinapril specifically interrupts the conversion of angiotensin I to angiotensin II in both plasma and tissue. Quinapril is enzymatically hydrolyzed to a pharmacologically active diacid form quinaprilat. Quinapril is efficacious in hypertensive models[1].
CAS Number
[85441-61-8]
Product Name Alternative
CI-906 (free acid)
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Angiotensin-converting Enzyme (ACE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)CC3=C(C=CC=C3)C1)O
Molecular Formula
C25H30N2O5
Molecular Weight
438.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Kaplan HR, et, al. Quinapril--a preclinical review of the pharmacology, pharmacokinetics, and toxicology. Angiology. 1989 Apr;40 (4 Pt 2) :335-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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