Quinapril

• Description :

  Quinapril is a potent, orally active, non-peptide and nonsulfhydryl inhibitor of angiotensin-converting enzyme (ACE) . Quinapril specifically interrupts the conversion of angiotensin I to angiotensin II in both plasma and tissue. Quinapril is enzymatically hydrolyzed to a pharmacologically active diacid form quinaprilat. Quinapril is efficacious in hypertensive models[1].

• Product Name Alternative :

  CI-906 (free acid)

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Angiotensin-converting Enzyme (ACE)

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C([C@H]1N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)CC3=C(C=CC=C3)C1)O

• Molecular Formula :

  C25H30N2O5

• Molecular Weight :

  438.52

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]Kaplan HR, et, al. Quinapril--a preclinical review of the pharmacology, pharmacokinetics, and toxicology. Angiology. 1989 Apr;40 (4 Pt 2) :335-50.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [85441-61-8]