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(S) -Doxazosin

CAT: 0804-HY-B0098CSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B0098CSize:1 Each
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Description
(S) -Doxazosin is a long-acting selective α1-adrenoceptor antagonist. (S) -Doxazosin exhibits antihypertensive activity through lowering total perioheral resistance by selective postsynaptic α1-blockade. (S) -Doxazosin reduces blood pressure in dog model with experimentally induced renal hypertension. (S) -Doxazosin can alleviate bladder outflow obstruction. (S) -Doxazosin can also be studied in mental health disorder-related research[1][2][3].
CAS Number
104874-86-4
Product Name Alternative
(S) -UK 33274
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@H]4OC5=CC=CC=C5OC4
Molecular Formula
C23H25N5O5
Molecular Weight
451.48
References & Citations
[1]Fulton, B., et al., (1995) . Doxazosin. An update of its clinical pharmacology and therapeutic applications in hypertension and benign prostatic hyperplasia. Drugs, 49 (2), 295-320. |[2]Young, R. A., & Brogden, R. N. (1988) . Doxazosin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in mild or moderate hypertension. Drugs, 35 (5), 525-541.|[3]Christie S. Richardson, et al., (2025) . Doxazosin for the treatment of mental health disorders: A scoping review. PLOS Mental Health.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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