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E3 ligase Ligand 64

CAT: 0804-HY-49385-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-49385-01Size:100 mg
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Description
E3 ligase Ligand 64 is a ligand for E3 ligase, used for the synthesis of RP03707.
CAS Number
2760850-50-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.52
Smiles
O=C1NC(CCN1C2=NN(C)C3=C2C=C(F)C(Br)=C3)=O
Molecular Formula
C12H10BrFN4O2
Molecular Weight
341.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.|[2]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported