E3 ligase Ligand 64

• Description :

  E3 ligase Ligand 64 is a ligand for E3 ligase, used for the synthesis of RP03707 (HY-176134) [1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Ligands for E3 Ligase

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  99.52

• Smiles :

  O=C1NC(CCN1C2=NN(C)C3=C2C=C(F)C(Br)=C3)=O

• Molecular Formula :

  C12H10BrFN4O2

• Molecular Weight :

  341.14

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.|[2]Ji X, et al. Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC. J Med Chem. 2025 May 8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  Store at room temperature 3 years

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [2760850-50-6]