7-Hydroxycarbostyril

• Description:

  7-Hydroxycarbostyril (7-Hydroxy-2 (1H) -quinolinone) (Compound 7) is a quinolinone derivative. 7-Hydroxycarbostyril can be used for synthesis of Brexpiprazole (HY-15780) . Brexpiprazole, a typical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor[1].

• Product Name Alternative:

  7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Drug Derivative

• Related Pathways:

  Others

• Field of Research:

  Others

• Purity:

  99.98

• Smiles:

  O=C1NC2=C (C=CC (O) =C2) C=C1

• Molecular Formula:

  C9H7NO2

• Molecular Weight:

  161.16

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Satheesh D, et al. Novel and facile process for the preparation of Brexpiprazole an antipsychotic drug[J]. Chemical Papers, 2024, 78 (5) : 3017-3022. |[2]Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25 (4) :505-11.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• CAS Number:

  70500-72-0