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7-Hydroxycarbostyril

CAT: 0804-HY-34763-01Size: 5 gDry Ice: NoHazardous: No
CAT#:HY-34763-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Hydroxycarbostyril (7-Hydroxy-2 (1H) -quinolinone) (Compound 7) is a quinolinone derivative. 7-Hydroxycarbostyril can be used for synthesis of Brexpiprazole (HY-15780) . Brexpiprazole, a typical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor[1].
CAS Number
[70500-72-0]
Product Name Alternative
7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative
Related Pathways
Others
Field of Research
Others
Purity
99.98
Smiles
O=C1NC2=C(C=CC(O)=C2)C=C1
Molecular Formula
C9H7NO2
Molecular Weight
161.16
Precautions
H302, H315, H319, H335
References & Citations
[1]Satheesh D, et al. Novel and facile process for the preparation of Brexpiprazole an antipsychotic drug[J]. Chemical Papers, 2024, 78 (5) : 3017-3022. |[2]Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25 (4) :505-11.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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