(E) -CLX-0921

• Description:

  (E) -CLX-0921 is the E-isomer of CLX-0921 (HY-19394) . CLX-0921 is an orally active PPARγ agonist with an IC50 of 1.54 μM. CLX-0921 has a potent antihyperglycemic activity, and can be used for the study of type 2 diabetes[1].

• UNSPSC:

  12352005

• Target:

  PPAR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease

• Purity:

  98.17

• Smiles:

  COC1=CC(OC)=CC(/C=C(C2=CC=C(C=C2)OC3=CC=C(C=C3)CC4SC(NC4=O)=O)/C(OC)=O)=C1

• Molecular Formula:

  C28H25NO7S

• Molecular Weight:

  519.57

• References & Citations:

  [1]Debendranath Dey, et al. A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential. Metabolism. 2003 Aug;52 (8) :1012-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [606932-81-4]