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LA-419

CAT: 0804-HY-19392Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19392Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LA-419 is an orally active nitric oxide (NO) donor. LA-419 can significantly reduce the amount of fecal worm eggs excreted, shorten the duration of egg excretion, and also decrease the number of larvae in the lungs and the number of parasitic females in the intestines in mice infected with S. venezuelensis. LA-419 can reduce the formation of atherosclerosis in apolipoprotein E-deficient mice. LA-419 can be used for the researches of infection and cardiovascular disease[1].
CAS Number
[263754-93-4]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
NO Synthase
Related Pathways
Immunology/Inflammation
Field of Research
Infection; Cardiovascular Disease
Smiles
[H][C@]12[C@]([C@@H](SC(C)=O)CO2)([H])OC[C@H]1O[N+]([O-])=O
Molecular Formula
C8H11NO6S
Molecular Weight
249.24
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Ruano AL, et al. Treatment with nitric oxide donors diminishes hyperinfection by Strongyloides venezuelensis in mice treated with dexamethasone. Acta Trop. 2015 Dec;152:90-95.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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