2-NAP

• Description :

  2-NAP is a major metabolite of polycyclic aromatic hydrocarbons (PAHs) . 2-NAP induces oxidative stress and inflammatory responses, impairs enamel formation, and disrupts oral microbiome balance, increasing the risk of early childhood caries (ECC) . 2-NAP is promising for research of development-related diseases such as childhood caries[1].

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Smiles :

  O=C(O)C[C@H](NS(=O)(C1=CC=C2C=CC=CC2=C1)=O)C(NCCC3=CC=CC=C3)=O

• Molecular Formula :

  C22H22N2O5S

• Molecular Weight :

  426.49

• References & Citations :

  [1]Patil SS, et al. Association of prenatal and early-life polycyclic aromatic hydrocarbons exposure with dental caries in childhood. Environ Res. 2025 Oct 1;282:122021.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [141577-40-4]