PAO-Nap

PAO-Nap

• CAS Number: 1613402-20-2
• UNSPSC Description: PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1].
• Target Antigen: Apoptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pao-nap.html
• Solubility: 10 mM in DMSO
• Smiles: O[As](C1=CC=C(NC(CCCCCN(C(C2=CC=C(N)C3=CC=CC4=C23)=O)C4=O)=O)C=C1)O
• Molecular Weight: 509.39
• References & Citations: [1]Yaping Liu, et al. Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase. J Med Chem. 2014 Jun 26;57(12):5203-11.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported