CV-6504

• Description :

  CV-6504 is a dual inhibitor of TXA2 synthase and 5-lipoxygenase. CV-6504 can scavenge ROS and exhibit antitumor activity. CV-6504 can be used for the researches of cancer, inflammation and cardiovascular disease[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Lipoxygenase; Prostaglandin Receptor

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research :

  Cancer; Inflammation/Immunology; Cardiovascular Disease

• Smiles :

  O=C1C(C)=C(C)C(C(C)=C1CC2=CC=CN=C2)=O

• Molecular Formula :

  C15H15NO2

• Molecular Weight :

  241.29

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Terao S, et al. Synthesis and biological evaluation of 2,3,5-trimethyl-6- (3-pyridylmethyl) -1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS) . Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:173-6.|[2]Hussey HJ, et al. Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6- (3-pyridylmethyl) 1,4-benzoquinone (CV-6504) . Br J Cancer. 1997;75 (6) :845-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  Phase 2

• Isoform :

  5-LOX; TXA2/TP

• CAS Number :

  [117574-40-0]