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CV-6504

CAT: 0804-HY-19064Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19064Size:1 Each
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Description
CV-6504 is a dual inhibitor of TXA2 synthase and 5-lipoxygenase. CV-6504 can scavenge ROS and exhibit antitumor activity. CV-6504 can be used for the researches of cancer, inflammation and cardiovascular disease[1][2].
CAS Number
117574-40-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Lipoxygenase; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C1C(C)=C(C)C(C(C)=C1CC2=CC=CN=C2)=O
Molecular Formula
C15H15NO2
Molecular Weight
241.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Terao S, et al. Synthesis and biological evaluation of 2,3,5-trimethyl-6- (3-pyridylmethyl) -1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS) . Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:173-6.|[2]Hussey HJ, et al. Mechanism of the anti-tumour effect of 2,3,5-trimethyl-6- (3-pyridylmethyl) 1,4-benzoquinone (CV-6504) . Br J Cancer. 1997;75 (6) :845-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
Phase 2
Isoform
5-LOX; TXA2/TP

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