MG-101 (GMP)

• Description:

  MG-101 (GMP) (Calpain inhibitor I (GMP) ) is MG-101 (HY-18964) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1].

• Product Name Alternative:

  Calpain inhibitor I (GMP) ; Ac-LLnL-CHO (GMP) ; ALLN (GMP)

• UNSPSC:

  12352211

• Target:

  Apoptosis; Proteasome

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C(N[C@H](C=O)CCCC)[C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C

• Molecular Formula:

  C20H37N3O4

• Molecular Weight:

  383.53

• References & Citations:

  [1]Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437 (2) :325-330.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  GMP Small Molecules

• Clinical Information:

  No Development Reported

• CAS Number:

  [110044-82-1]