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Antibacterial agent 301

CAT: 0804-HY-179405Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179405Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antibacterial agent 301 (compound 14c) is a pyridine-amide pleuromutilin derivative with broad-spectrum antibacterial and pronounced antimycoplasmal activity. Antibacterial agent 301 inhibits peptidyl transferase center (PTC), breaks down biofilms, and disrupts cell membranes in multidrug-resistant (MDR) bacteria. Antibacterial agent 301 exhibits activity in a systemic methicillin-resistant Staphylococcus aureus (MRSA) infection mouse model. Antibacterial agent 301 can be used for MDR bacterial infection research[1].
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(O[C@@H]1C[C@](C=C)(C)[C@@H](O)[C@H](C)[C@]2(CCC3=O)[C@]3([H])[C@@]1(C)[C@H](C)CC2)CSC4=C(NC([C@@H](N)CC(C)C)=O)C=NC=C4
Molecular Formula
C33H49N3O5S
Molecular Weight
599.82
References & Citations
[1]Zhang L, et al. Conformationally restricted pleuromutilins via a pyridinyl-amide tether bias peptidyl transferase center engagement enabling broad-spectrum potency against multidrug-resistant bacteria. Eur J Med Chem. 2026 Jan 15;302 (Pt 2) :118316.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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