EEF1A2-IN-1

• Description :

  EEF1A2-IN-1 is a potent and covalen EEF1A2 inhibitor. EEF1A2-IN-1 exhibits selective antiproliferative activity against osteosarcoma (OS) cells. EEF1A2-IN-1 induces apoptosis by inhibiting EEF1A2 and downregulating the AKT signaling pathway. EEF1A2-IN-1 inhibits tumor growth in a xenograft mouse model. EEF1A2-IN-1 can be used for the research of OS[1].

• UNSPSC :

  12352005

• Target :

  Akt; Apoptosis

• Related Pathways :

  Apoptosis; PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Smiles :

  C=CC(NC(C1=CC=C(C=C1)C2=CC=C(C=C2)O)C(OC)=O)=O

• Molecular Formula :

  C18H17NO4

• Molecular Weight :

  311.33

• References & Citations :

  [1]Xue J, et al. Identification of EEF1A2 as a potential therapy target of osteosarcoma using novel compound 8e. Eur J Med Chem. 2026;302 (Pt 3) :118355.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported